Electromechanical Coupling During the Activation of Cav1.2

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Electromechanical coupling I. Introduction.

In skeletal muscle fibres contraction is initiated by the action potential which travels inward along the transverse tubular system and causes in some way the release of Ca from the terminal cisternae of the sarcoplasmic reticulum (SR). Ca-release is probably controlled by a potential-sensor (intram em brane charge movement) in the wall of the T-system which in a triad is about 10 20 nm apart f...

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ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2010

ISSN: 0006-3495

DOI: 10.1016/j.bpj.2009.12.2808